Fluid Behind the Retina: Causes, Diagnosis and Treatment

2021-12-24 10:14:45 By : Ms. Selina Zhang

Bryan Wolynski, OD, is a board-certified community optometrist who has been in the eye care field for over 30 years. He works in private practice in New York City.

The retina at the back of the eye is the tissue you rely on for sight. The eyes themselves are fed by numerous blood vessels and filled with fluid. Sometimes, though, there can be problems. Fluid can build up behind the retina due to different conditions, including macular edema and central serous retinopathy .

Here's what to know to recognize what may be causing fluid underneath the retina and the steps you need to take for appropriate diagnosis and treatment.

More than one thing can cause fluid to build up behind the retina. So it's important to take a closer look to determine the reason in your case.

With macular edema, fluid builds up in an area of the retina known as the macula. This is the area that you rely on for sharp central vision. If fluid builds up underneath, it can get distorted as the tissue swells.

Fluid leakage can come from damaged blood vessels nearby in the retina. This can be the result of a number of different conditions. Macular edema can be caused by any disease that damages blood vessels and can even result from eye surgery.

With central serous retinopathy, fluid can build up under the retina. The retinal pigment epithelium (RPE), which is between the choroid and the retina, stops functioning as it should. Without this working right, fluid begins to build up under the retina.

This can cause visual distortion and even a slight retinal detachment in some cases. Those most at risk for this condition are men ranging in age from their 30s to their 50s, people with type A personalities, those taking steroids, and people with autoimmune disorders.

Cases of diabetic retinopathy result from the elevated blood sugar that occurs in those who have diabetes. Over time, high amounts of sugar in the blood can damage the retina by affecting the blood vessels. The blood vessels swell, and the tight junctions in them break down, leading to bleeding or leaking fluid.

Also, glycosylated red blood cells (which have sugar bound to the hemoglobin) do not bring enough oxygenated blood. This triggers the formation of new blood vessels. These, however, are fragile and easily leak and bleed further. This leads to more fluid behind the retina and ultimately may end up in a detachment.

The choroid is a layer of spongy blood vessels between the retina and the white part of your eyes, known as the sclera. The role of the choroid is to deliver nutrition and oxygen to the outside portion of the retina.

If fluid or blood (choroidal effusion) gets between the choroid and sclera, it can lead to a detachment, known as serous choroidal detachments. These are generally related to low intraocular pressure, usually following recent glaucoma surgery.

This decrease in pressure allows the fluid to accumulate in the space around the cells while the capillaries become more permeable due to inflammation.

To determine if you may have fluid beneath the retina, your eye doctor will thoroughly examine your eyes. Some of the tests they will likely use may include:

An Amsler grid test is an easy way to determine if your all-important central vision has changed. With this test, you simply look at the grid-like squares and tell the doctor whether any of the lines look wavy or if there are any missing areas. This can help to detect even minor vision changes.

Optical coherence tomography takes cross-sectional pictures of your retina with a special camera. It can measure retinal thickness and detect fluid beneath the retina and swelling. With this information, your doctor can determine whether you need treatment for any fluid trapped under the retina.

With autofluorescence imaging, the idea is to make use of the retina's naturally occurring fluorescence. Even without injecting any dye, when a blue light is used to illuminate the retina, certain structures glow.

These glowing structures can be captured in a black and white image. Characteristic patterns may then indicate that diseases like age-related macular degeneration or central serious retinopathy are progressing and can help indicate appropriate treatment.

Fluorescein angiography can be used to diagnose swelling in the retina. With this, a yellow fluorescein dye is injected into your arm. When it reaches your eyes a few seconds later, it will cause them to shine brightly. A special camera can then be used to take pictures of the area. These can alert your doctor about what type of treatment is needed and where.

With indocyanine green angiography , the dye works similarly to fluorescein but only can be viewed in infrared light. Also, it circulates deeper into the retinal layers where they can be photographed with an infrared-sensitive camera. This is often used for choroidal angiography to complement fluorescein angiography of the retina.

With this test, also known as a b-scan ultrasound, sound waves are used to create a picture of structures within the eye. This technique can be used to detect complications such as retinal detachment, diabetic retinopathy, and eye cancers.

Deciding on the best treatment for any particular case of fluid behind the retina will be based on the cause here. Some possible treatment approaches include the following:

Fluid beneath the retina can occur due to inflammation or leaking blood vessels in conditions such as diabetic retinopathy, macular edema, central serous retinopathy, and choroidal effusion. An eye doctor will perform an eye exam and may use various imaging methods to assess the problem.

Treatment depends on the condition causing the fluid buildup. Anti-inflammatory medications, surgery, laser treatment, anti-VEGF injections, or lifestyle changes may be used.

Fluid beneath the retina can come from a variety of sources. The good news is once practitioners figure out what may be at the root in your particular case, there are many different treatments that may alleviate this and help to preserve your vision.

This depends on the cause. Once this is diagnosed, you may simply be given medication to tamp-down inflammation, or may need to undergo laser treatment to seal blood vessels, or may need some treatment with anti-VEGF injections, among other possibilities.

It is possible. Fluid behind the retina can sometimes lead to a retinal detachment, pushing the retina away as it collects. This is known as an exudative retinal detachment. If the detachment is not promptly treated and is extensive enough, this can cause permanent vision loss.

While it may not cause vision loss in all cases, fluid behind the eye is not normal. Therefore, it is important to promptly see a doctor and find out what is causing this so it can be treated.

Yes, eating fiber-rich fruits like bananas, apples, and berries, which are metabolized more slowly and lead to fewer blood sugar fluctuations, are helpful for macular degeneration. Also suitable are high-fiber vegetables like broccoli, corn, carrots, leafy greens, legumes and beans, and whole grains.

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American Academy of Ophthalmology. What causes macular edema?

American Academy of Ophthalmology. Central serous retinopathy.

American Diabetes Association. Eye complications.

Schrieber, C, Liu, Y. Choroidal effusions after glaucoma surgery. Curr Opin Ophthalmol. 2015; 26(2):134–142. doi:10.1097/ICU.0000000000000131

American Academy of Ophthalmology. What is optical coherence tomography.

The University of British Colombia. Autofluorescence imaging.

American Academy of Ophthalmology. What is fluoroscein angiography.

University of Iowa. Indocyanine green angiography.

Retina Macula Institute. Ocular ultrasound.

National Eye Institute. Macular edema.

National Eye Institute. Diabetic retinopathy.

American Academy of Ophthalmology. Anti-VEGF treatments.

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